Dendrimer-coupled sonophoresis-mediated transdermal drug-delivery system for diclofenac

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Dendrimer-coupled sonophoresis-mediated transdermal drug-delivery system for diclofenac

The purpose of the present study was to develop a novel transdermal drug-delivery system comprising a polyamidoamine dendrimer coupled with sonophoresis to enhance the permeation of diclofenac (DF) through the skin. The novel transdermal drug-delivery system was developed by using a statistical Plackett-Burman design. Hairless male Wistar rat skin was used for the DF-permeation study. Coupling ...

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ژورنال

عنوان ژورنال: Drug Design, Development and Therapy

سال: 2015

ISSN: 1177-8881

DOI: 10.2147/dddt.s75702